Search - Fakultät Statistik - TU Dortmund

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1. GRK 2624
2. Research
3. Projects
I3: Enrich

in which genes are grouped according to their involvement in biological processes or molecular functions. If many genes of a biologically defined gene group are expressed significantly differently between [...] between, e.g., measurements at two different concentrations, this suggests that the corresponding biological function might be intensified or weakened by the higher concentration (Goeman and Mansmann, 2008) [...] n of statistical significance of the gene groups provides a global molecular profile with high biological interpretability, also with regard to structural, regulatory or enzymatic properties of the associated …
1. Genetik
2. Chair
3. Team
Prof. Dr. Jörg Rahnenführer - TU Dortmund

n (Bioinformatics), Saarland University, Saarbrücken, 2006 Thesis: Statistical methods for the biological interpretation of genome-wide measurements Dr.rer.nat. (Mathematics), Heinrich Heine University [...] Genetics and Chemometrics, TU Dortmund Oct 2002 - Mar 2007: Postdoc, Department of Computational Biology and Applied Algorithmics, Max Planck Institut for Informatics , Saarbrücken, Germany Oct 2001 - Sep [...] relationships Statistical analysis of genomic data for cancer diagnosis and therapy Methods for biological interpretation of gene expression data Statistical analysis of data from proteomics Analysis of …
1. Department of Statistics
2. Research
3. Areas
Biostatistics

initially understood to mean statistical theory and methods for describing, analyzing, and interpreting biological data. Today, we see a much broader field of activity in biometrics with applications in all life [...] Bioinformatics is a broad field of research and is essentially concerned with the analysis of biological data at the molecular level. Numerous new experimental techniques are continuously being developed [...] innumerable features are measured simultaneously. This hypothesis-generating character of molecular biology experiments constantly places new demands on the statistical analysis of experimental results. Toxicology …
1. Genetik
2. Research
Projects

logischen in vitro Testmethoden in die Anwendung (Transfer of in vitro test methods for systems biology-based developmental toxicology into application) (02/2017-01/2020) BMBF joint application, LivSy [...] the toxome of cultivated human hepatocytes (12/2013-11/2015) BMBF joint application, SysDT Systems biology-based prediction of developmental toxicity (01/2014-06/2016) DFG individual application (jointly [...] Stammzelldifferenzierung (Statistical quantification and modelling of changes in gene expression and biological processes in stem cell differentiation) (01/2022-12/2024) Marco Grzegorczyk: DFG individual application …
1. Genetik
Research

relationships Statistical analysis of genomic data for cancer diagnosis and therapy Methods for biological interpretation of gene expression data Statistical analysis of data from proteomics Analysis of …
1. Compstat
Professorship

Co-Supervisor: Anne Meyer Room: Vogelpothsweg 87, Room 712 Daniel Habermann Background: Computational Biology Project: Amortized Bayesian Inference for Multilevel Models Email: daniel.habermann tu-dortmund de [...] Email: florence.bockting tu-dortmund de Room: Vogelpothsweg 87, Room 711 Luna Fazio Background: Biology and Statistics Project: Bayesian Distributional Latent Variable Models Email: luna.fazio tu-dortmund …
1. Compstat
2. Professorship
Team

tu-dortmund de Room: Vogelpothsweg 87, Room 721 PostDocs Daniel Habermann Background: Computational Biology Project: Amortized Bayesian Inference for Multilevel Models Email: daniel.habermann tu-dortmund de [...] Email: florence.bockting tu-dortmund de Room: Vogelpothsweg 87, Room 711 Luna Fazio Background: Biology and Statistics Project: Bayesian Distributional Latent Variable Models Email: luna.fazio tu-dortmund …
1. GRK 2624
2. Research
3. Projects
I4: Omics-LongInt

only a few or no replicates, and therefore, do not take into account the heterogeneity between biological replicates. We, however, recently modified the externally centred correlation coefficient and the [...] multiplicatively, and instead of a general gene network, a more specific subnetwork adapted to the biological/toxicological problem at hand should be generated and used in the conditional autoregressive prior [...] data identifies Alzheimer's disease candidate genes and networks. To appear in: PLOS Computational Biology. Klein HU, Schäfer M, Porse BT, Hasemann MS, Ickstadt K, Dugas M (2014). Integrative analysis of …
1. GRK 2624
2. Research
3. Projects
P12: ValuesBelowLimit

entries one cannot distinguish whether a certain feature (e.g. an analyte) was actually absent (biological reason) or whether its value is below the lower limit of quantification or detection (technical [...] models are known to have their limitations, such as a lack of power, or that they focus only on the biological or technical reason for potential zeros (van Reenen et al., 2017). In this project, we initially [...] identified k nearest neighbours also has a zero value, then the feature of interest is classified as biologically not available and represented by an actual zero. If the pre-defined proportion of zeros is not …
1. Fakultät Statistik
2. News: 6/14/2024
"Causality" professorship at the Research Center Trustworthy Data Science and Security filled

statistics and computer science and also on interdisciplinary projects with partners from medicine, biology and psychology." Marx previously worked in Saarbrücken, Amsterdam, Zurich and Basel. For his doctorate [...] analyzed machine learning models for biomedical applications in HIV disease at the Computational Biology Group at ETH Zurich. He has also been a member of the European Laboratory for Learning and Intelligent …

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